Microfluidic Mixing


Microfluidic Mixing

Microfluidics have received much attention in recent years, since there are substantial benefits to be gained from its characteristics of lower cost, smaller size and less consumption of reagents and samples compared with common macrofluidic systems. Micromixers are one of the most promising applications of microfluidic systems and have been widely used in industries, ranging from biological detection analysis to chemical reaction processes. Based on the mechanism applied in the microfluidic mixing process, it’s generally accepted that micromixers can be categorized as ‘active’ and ‘passive’ types depending on whether the cause of mixing is geometric particularity or external agitation, respectively.

The ability to rapidly mix liquids greatly improves the performance of microfluidic systems. Unfortunately, the fluid flow is laminar inside a microfluidic channel due to its micron size, where the characteristic Reynolds number is very small. Therefore, different analytes need longer mixing time in microchannel since the mixing is mainly governed by the slow diffusion process without turbulence. This gives rise to the need for rapid mixing in microfluidic devices, so improving the efficiency of micromixers has generated considerable recent research interest. Researchers have been designing efficient microfluidic mixing systems for both active and passive categories. Numerous experiments can be established and investigated to improve the mixing efficiency of different reagents and samples during biological and chemical reaction processes. The simulation of computational fluid dynamics (CFD) has also been proposed as a strong tool to validate and explain the physical phenomena to optimize the hardware design of micromixers.

The current Research Topic covers both experimental and simulated studies on novel microfluidic mixing design, and mechanisms of various active and passive micromixers, including:

• Novel design and study of active or passive micromixers
• Experimental and/or numerical, simulation studies of microfluidic mixing processes, including flow phenomenon and/or heat transfer characteristics
• Incorporation of various external fields to drive micro-mixing, such as magnetic, acoustic, electrokinetic fields, etc.
• Various applications of micromixers in biological and chemical reactions, food industries, etc.

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Nimmi Anna
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Allied Journal of Medical Research
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