Collagen thin film glucose biosensor


Collagen thin film glucose biosensor

A biosensor is an analytical device, used for the detection of an analyte that combines a biological component with a physicochemical detector. Here the biosensor using chrome shavings, chrome containing leather waste in tannery, based collagen from tannery solid waste is characterized for bio sensing application such as glucose detector. The electrical and electronic characteristics obtained using cyclic voltmeter (CV) reveals, the sensitivity of 2µA/V/gm Zinc oxide nanoparticles and 2 mA/V / 1.5gm. We prepared two solutions of glucose i.e., 3mM and 17 mM. The resulting voltage for concentrations below 4 mM (70mg/dL) hypoglycemic or above 10mM (180mg/dL) is considered to be hyperglycemic respectively. The voltage for these concentrations recorded was 270mV (70 mV/mM) and 860mV (86 mV/mM). After approximately 5 seconds the solution was placed on the ZnO collagen glucose sensor the voltage peaked at 270mV for the 3mM glucose solution and 860mV for the 17mM glucose solution. Thus, using the byproduct of tanning industry, a biosensor can be fabricated for biomedical application.

In this study the Zinc Oxide Nanoparticles and Collagen based thin film Sheet generates current of 4 µA and voltage of 4 mA, Also shows that as the concentration of the zinc oxide nano particle increases there is a marginal change in the current output. The resulting voltage of Biosensor strips for the experiments in response to the 2.8mM solution and 16.7mM solution are recorded. The voltage peaked at 280mv for the 2.8mM solution (hypoglycemia) and 860mv for the 16.7mM solution (hyperglycemias) shows 9.4 mV per mM solution.The solution of higher concentration resulted in a higher spike in voltage. This biosensor is made as a bench scale model and further standardization and calibration is to be repeated for pilot scale production. The accuracy of the reading is less than 0.2 % error. The product is cost effective and further it can be reduced when it is made in a large scale. The market price of the product is rupees 45, our price will be rupees 20. In this study, we not only reduce the environmental pollution but also recycle the waste leather into the value added product, which helps in “Green and Advanced Technology for the Environment Sustainability [GATES]”

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